Latvian Registry of Familial Hypercholesterolemia

Description

The Latvian Registry of Familial Hypercholesterolaemia (FH) is a nationwide registry established in 2015. Referrals are coordinated via a central coordinator phone line, providing access to consultations with cardiologists specialised in lipidology. Since 2025, pilot programmes of universal and opportunistic screening have been conducted within the framework of the Joint Action on CARdiovascular diseases and DIabetes (JACARDI). The registry also captures other primary dyslipidaemias—notably elevated lipoprotein(a) [Lp(a)] and severe hypertriglyceridemia - and collaborates with the Genome Database of the Latvian Population (LGDB) and paediatric endocrinologists, with ongoing international engagement.

Program launch date

Since 2015

Responsible entity

Mostly research grants.

Available results and quality metrics

More than 1500 patients in database. Estimated 10% FH cases detected.

Limitations / comments

There is currently no state-funded national programme, and reimbursement for genetic testing is limited; a dedicated paediatric FH registry is needed.